Table 3.
Association between IgG responses to PfRh5 and PfRipr and incidence of malaria clinical episodes.
| PfRh5 |
PfRipr |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M vs L |
H vs L |
M vs L |
H vs L |
|||||||||
| IRR | 95% CI | P | IRR | 95% CI | P | IRR | 95% CI | P | IRR | 95% CI | P | |
| Unadjusted | 0.55 | (0.35–0.85) | <0.01 | 0.21 | (0.12–0.39) | <0.01 | 1.03 | (0.64–1.65) | 0.90 | 0.81 | (0.49–1.33) | 0.41 |
| Adjusted | 0.54 | (0.34–0.84) | <0.01 | 0.26 | (0.13–0.49) | <0.01 | 1.05 | (0.65–1.69) | 0.83 | 0.87 | (0.53–1.44) | 0.58 |
Incidence rate ratios (IRR) were determined to assess associations between antibody responses and overall incidence of clinical episodes for all individuals. Values represent unadjusted and adjusted ratios (age and location) ± 95% confidence intervals (CI). Significant associations are shown in bold.