Table 1.

Volume of activation in response to almond odor.

Region of interest (ROI)	Wild-type			Heter zQ175			Homo zQ175
	Med	Max	Min	Med	Max	Min	Med	Max	Min	p Value
Medial amygdaloid area	4	20	0	2	10	0	0	0	0	0.002
Ventral medial hypothalamic area	7	68	0	13	33	0	0	0	0	0.004
Frontal association ctx	10	23	3	0	14	0	0	11	0	0.006
Subiculum	3	27	0	1	4	0	0	2	0	0.008
Anterior hypothalamic area	3	27	0	4	14	0	0	0	0	0.008
Vestibular area	8	62	0	0	8	0	0	3	0	0.009
Endopiriform area	4	21	0	0	3	0	0	0	0	0.011
Extended amydala	1	11	0	0	3	0	0	0	0	0.012
Dentate gyrus	6	32	0	1	7	0	0	4	0	0.016
Anterior cingulate area	4	28	0	0	8	0	0	3	0	0.026
Lateral caudal hypothalamic area	4	39	0	4	25	0	0	11	0	0.026
Lateral posterior thalamic area	3	27	0	0	0	0	0	33	0	0.027
Primary somatosensory ctx	4	21	2	4	18	0	0.5	5	0	0.03
Secondary somatosensory ctx	1	14	0	3	6	1	0	4	0	0.032
Glomerular layer	6	29	1	3	40	1	0.5	10	0	0.044
Locus ceruleus	20	50	0	0	31	0	0	33	0	0.045
Principal sensory nucleus trigeminal	1	21	0	1	6	0	0	1	0	0.048
Medial mammillary area	23	82	0	3	31	0	0	35	0	0.059

Shown is a truncated list of 116 brain areas and their median (med), maximum (max), and minimum (min) number of voxels as a percentage of the total ROI volume (i.e., number of voxels activated, divided by the total number of voxels in the 3D volume of interest, times 100) for wild-type, HET, and HOMzQ175 mice following exposure to odor of almond. These volumes of activation for each brain region across genotypes were analyzed using a Newman–Keuls multiple comparisons test statistic and rank order for their significance. p Values are presented on the far right column. The shaded gray columns highlight the median number of voxels for each ROI and each genotype to aid in visual comparisons.