Table 2.
Cytotoxicity (IC50 in μM)a of compounds 1–10 isolated C. scoparia.
| IC50 (μM) | |||
|---|---|---|---|
| Cell lines Compound |
HeLa | MCF-7 | HepG2 |
| 1 | 3.21 ± 0.21 | 4.23 ± 0.11 | 3.91 ± 0.54 |
| 2 | 0.079 ± 0.03 | 0.32 ± 0.08 | 0.64 ± 0.12 |
| 3 | 11.98 ± 1.79 | 12.21 ± 1.81 | 13.39 ± 1.3 |
| 4 | 13.54 ± 2.1 | 12.96 ± 1.57 | 14.24 ± 1.21 |
| 5 | 0.11 ± 0.02 | 0.14 ± 0.04 | 0.25 ± 0.05 |
| 6 | 8.14 ± 1.28 | 6.52 ± 1.40 | 4.4 ± 0.50 |
| 7 | 9.31 ± 0.91 | 11.33 ± 1.12 | 12.41 ± 0.94 |
| 8 | 1.12 ± 0.74 | 5.93 ± 1.12 | 4.2 ± 1.30 |
| 9 | 1.71 ± 0.18 | 7.75 ± 1.31 | 5.7 ± 0.85 |
| 10 | 3.54 ± 1.89 | 9.98 ± 1.89 | 7.14 ± 1.97 |
| Deguelin | 6.21 ± 0.82 | 5.17 ± 0.94 | 0.65 ± 0.11 |
aThe data shown are means ± SD obtained from three independent experiments.