Table 2.
Pain and Impact on Daily Living Within the Past 3 Months by eGFR Level
| All (N=1043) |
Males (n=517) | Females (n=526) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| eGFR>60 (n=303) |
eGFR 45–60 (n=108) |
eGFR 20–44 (n=106) |
All | p value ^ |
eGFR >60 (n=306) |
eGFR 45–60 (n=113) |
eGFR 20–44 (n=107) |
All | p value^ |
||
| Back pain frequency |
0.6 | 0.2 | |||||||||
| Never-rarely | 491(49.0%) | 155(54.0%) | 64(59.8%) | 54(52.4%) | 273(54.9%) | 138(47.1%) | 40(36.7%) | 40(38.8%) | 218(43.2 %) |
||
| Sometimes | 298(29.7%) | 85(29.6%) | 29(27.1%) | 28(27.2%) | 142(28.6%) | 83(28.3%) | 40(36.7%) | 33(32.0%) | 156(30.9 %) |
||
| Often-usually-always | 213(21.3%) | 47(16.4%) | 14(13.1%) | 21(20.4%) | 82(16.5%) | 72(24.6%) | 29(26.6%) | 30(29.1%) | 131(25.9 %) |
||
| Back pain intensity on average# |
2.0[1.0–3.0] (n=775) |
1.0(1.0–3.0) (n=218) |
2.0(1.0–3.0) (n=79) |
2.0(1.0–3.0) (n=80) |
2.0(1.0–3.0) (n=377) |
0.3b | 2.5(1.0–4.0) (n=222) |
2.0(1.0–4.0) (n=85) |
2.0(1.0–4.0) (n=91) |
2.0(1.0–4.0) (n=398) |
0.4b |
| Back pain associated with gross hematuria |
39(5.0%) | 12(5.5%) | 5(6.2%) | 4(4.9%) | 21(5.5%) | 0.9a | 10(4.5%) | 3(3.6%) | 5(5.5%) | 18(4.5%) | 0.8a |
| Radiculopathy frequency |
0.08 | 0.1 | |||||||||
| Never-rarely | 814(81.9%) | 244(85.3%) | 94(90.4%) | 88(86.3%) | 426(86.6%) | 229(79.0%) | 82(74.5%) | 77(75.5%) | 388(77.3 %) |
||
| Sometimes | 125(12.6%) | 29(10.1%) | 9(8.7%) | 14(13.7%) | 52(10.6%) | 39(13.5%) | 14(12.7%) | 20(19.6%) | 73(14.5%) | ||
| Often-usually-always | 55(5.5%) | 13(4.5%) | 1(1.0%) | 0(0.0%) | 14(2.8%) | 22(7.6%) | 14(12.7%) | 5(4.9%) | 41(8.2%) | ||
| Radicular pain intensity# on average |
3.0(1.0–5.0) (n=336) |
3.0(1.0–5.0) (n=84) |
2.0(1.0–3.0) (n=28) |
3.5(1.5–6.5) (n=32) |
3.0(1.0–5.0) (n=144) |
0.08b | 4.0(2.0–6.0) (n=105) |
4.0(1.0–7.0) (n=41) |
4.0(2.0–6.0 (n=46) |
4.0(2.0–6.0) (n=192) |
0.9b |
| Abdominal pain frequency |
0.05* | 0.8 | |||||||||
| Never-rarely | 716(72.0%) | 239(83.9%) | 85(79.4%) | 81(78.6%) | 405(81.8%) | 181(62.4%) | 70(64.2%) | 60(59.4%) | 311(62.2 %) |
||
| Sometimes | 160(16.1%) | 30(10.5%) | 10(9.3%) | 7(6.8%) | 47(9.5%) | 62(21.4%) | 25(22.9%) | 26(25.7%) | 113(22.2 %) |
||
| Often-usually-always | 119(12.0%) | 16(5.6%) | 12(11.2%) | 15(14.6%) | 43(8.7%) | 47(16.2%) | 14(12.8%) | 15(14.8%) | 76(15.2%) | ||
| Abdominal pain intensity# on average |
2.0(1.0–3.0) (n=480) |
2.0(1.0–3.0) (n=97) |
1.0(1.0–3.0) (n=39) |
2.0(1.0–3.0) (n=47) |
2.0(1.0–3.0) (n=183) |
0.4b | 2.0(1.0–3.0) (n=175) |
2.0(1.0–4.0) (n=56) |
2.0(1.0–4.0) (n=66) |
2.0(1.0–4.0) (n=297) |
0.9b |
| Treatment for pain | |||||||||||
| No treatment | 586(56.5%) | 195(64.6%) | 75(70.1%) | 66(62.9%) | 336(65.4%) | 0.4 | 147(48.4%) | 54(47.8%) | 49(46.2%) | 250(47.8 %) |
0.9 |
| OTC Medications |
305(29.4%) | 62(20.5%) | 26(24.3%) | 30(28.6%) | 118(23.0%) | 0.2 | 110(36.2%) | 39(34.5%) | 38(35.9%) | 187(35.8 %) |
0.9 |
| Prescription pain medications |
125(12.0%) | 28(9.3%) | 6(5.6%) | 11(10.5%) | 45(8.7%) | 0.4 | 40(13.2%) | 20(17.7%) | 20(18.9%) | 80(15.3%) | 0.2 |
| Acupuncture, heat or cold, massage therapy |
113(10.8%) | 23(7.6%) | 7(6.5%) | 6(5.7%) | 36(7.0%) | 0.8 | 45(14.7%) | 17(15.0%) | 15(14.0%) | 77(14.6%) | 0.9 |
| Surgical procedure |
4(0.4%) | 0(0.0%) | 0(0.0%) | 0(0.0%) | 0(0%) | --- | 2(0.7%) | 0(0.0%) | 2(1.9%) | 4(0.8%) | 0.2a |
| Pain affected physical ability to do what you want to |
0.2 | 0.4 | |||||||||
| Completely/very dissatisfied |
80(17.8%) | 16(16.2%) | 9(25.7%) | 8(19.5%) | 33(18.9%) | 27(17.1%) | 10(17.2%) | 10(16.9%) | 47(17.1%) | ||
| Somewhat dissatisfied |
79(17.6%) | 13(13.1%) | 5(14.3%) | 12(29.3%) | 30(17.1%) | 23(14.6%) | 11(19.0%) | 15(25.4%) | 49(17.8%) | ||
| Somewhat satisfied |
96(21.3%) | 20(20.2%) | 6(17.1%) | 8(19.5%) | 34(19.4%) | 39(24.7%) | 9(15.5%) | 14(23.7%) | 62(22.5%) | ||
| Completely/very satisfied |
195(43.3%) | 50(50.5%) | 15(42.9%) | 13(31.7%) | 78(44.6%) | 69(43.7%) | 28(48.3%) | 20(33.9%) | 117(42.5 %) |
||
| Pain interfered moderately to extremely with: |
|||||||||||
| Mood | 159(16.0%) | 41(14.4%) | 8(17.5%) | 14(14.1%) | 63(12.9%) | 0.1 | 55(18.8%) | 19(17.4%) | 22(21.8%) | 96(19.1%) | 0.7 |
| Relations with others |
103(10.4%) | 22(7.7%) | 5(4.7%) | 8(8.0%) | 35(7.19%) | 0.5 | 41(14.0%) | 11(10.0%) | 16(15.8%) | 68(13.5%) | 0.4 |
| Walking ability | 120(12.1%) | 25(8.8%) | 4(3.8%) | 12(12.0%) | 41(8.4%) | 0.1 | 36(12.3%) | 20(18.3%) | 23(22.8%) | 79(15.7%) | 0.03 * |
| Sleep | 206(20.8%) | 48(16.9%) | 13(12.4%) | 19(19.2%) | 80(16.4%) | 0.4 | 70(23.9%) | 29(26.6%) | 27(26.7%) | 126(25.1 %) |
0.7 |
| Work | 129(13.1%) | 29(10.2%) | 4(3.8%) | 14(14.0%) | 47(9.6%) | 0.04* | 47(16.5%) | 15(13.9%) | 20(20.2%) | 82(16.7%) | 0.4 |
| Strenuous physical activity |
198(21.1%) | 38(14.2%) | 15(14.3%) | 25(25.5%) | 78(16.6%) | 0.02* | 60(22.4%) | 29(28.4%) | 31(32.3%) | 120(25.7 %) |
0.1 |
| Social activities or hobbies |
107(11.5%) | 20(7.5%) | 2(1.9%) | 12(12.5%) | 34(7.3%) | 0.02* | 43(16.0%) | 13(12.9%) | 17(18.1%) | 73(15.8%) | 0.6 |
| Enjoyment of life |
140(14.2%) | 34(12.0%) | 10(9.4%) | 13(13.1%) | 57(11.7%) | 0.6 | 41(14.1%) | 19(17.4%) | 23(22.8%) | 83(16.6%) | 0.1 |
Note: Note: eGFRs expressed in mL/min/1.73 m2. Values for categorical variables are given as number (percentage); values for continuous variables, as median [interquartile range], with numbers of participants with data indicated.
eGFR, estimated glomerular filtration rate; OTC, over the counter.
#
Pain Intensity Score is based on a visual analog scale with 0 as “No pain” and 10 as “Pain as bad as you can imagine”.
*
Significant p value of ≤0.05
^
P values across eGFR groups