Table II.
Sensitivity, specificity, and positive likelihood ratio of the Generalized Anxiety Disorder-7 (GAD-7) and GAD-2 scales.
| Cut-off point | Generalized anxiety disorder (n = 6 [4.0%]) |
Panic disorder (n = 10 [6.7%]) |
Other anxiety disorder (n = 10 [6.7%]) |
| GAD-7 score | |||
| ≥ 5 | |||
| Sensitivity (95% CI) | 1.00 (0.54–1.00) | 0.70 (0.35–0.94) | 0.80 (0.44–0.98) |
| Specificity (95% CI) | 0.73 (0.65–0.80) | 0.73 (0.65–0.80) | 0.74 (0.66–0.81) |
| Positive LR (95% CI) | 3.69 (2.82–4.83) | 2.58 (1.58–4.20) | 3.03 (2.00–4.59) |
| ≥ 6 | |||
| Sensitivity (95% CI) | 1.00 (0.54–1.00) | 0.70 (0.35–0.93) | 0.70 (0.35–0.93) |
| Specificity (95% CI) | 0.79 (0.72–0.86) | 0.79 (0.72–0.86) | 0.79 (0.72–0.86) |
| Positive LR (95% CI) | 4.80 (3.49–6.60) | 3.38 (2.01–5.68) | 3.38 (2.01–5.68) |
| ≥ 7 | |||
| Sensitivity (95% CI) | 1.00 (0.54–1.00) | 0.60 (0.26–0.88) | 0.60 (0.26–0.88) |
| Specificity (95% CI) | 0.83 (0.75–0.88) | 0.82 (0.75–0.88) | 0.82 (0.75–0.88) |
| Positive LR (95% CI) | 5.76 (4.03–8.23) | 3.36 (1.81–6.24) | 3.36 (1.81–6.24) |
| ≥ 8 | |||
| Sensitivity (95% CI) | 0.83 (0.36–0.99) | 0.40 (0.12–0.74) | 0.50 (0.19–0.81) |
| Specificity (95% CI) | 0.88 (0.82–0.93) | 0.87 (0.80–0.92) | 0.88 (0.81–0.93) |
| Positive LR (95% CI) | 7.06 (3.98–12.50) | 3.11 (1.30–7.45) | 4.12 (1.92–8.83) |
| ≥ 9 | |||
| Sensitivity (95% CI) | 0.83 (0.36–0.99) | 0.40 (0.12–0.74) | 0.40 (0.12–0.74) |
| Specificity (95% CI) | 0.94 (0.89–0.97) | 0.93 (0.87–0.97) | 0.93 (0.87–0.97) |
| Positive LR (95% CI) | 13.3 (6.45–27.6) | 5.60 (2.13–14.70) | 5.60 (2.13–14.70) |
| ≥ 10 | |||
| Sensitivity (95% CI) | 0.67 (0.22–0.96) | 0.40 (0.12–0.74) | 0.40 (0.12–0.74) |
| Specificity (95% CI) | 0.95 (0.90–0.98) | 0.95 (0.90–0.98) | 0.95 (0.90–0.98) |
| Positive LR (95% CI) | 13.7 (5.48–34.3) | 8.00 (2.81–22.80) | 8.00 (2.81–22.80) |
| GAD-2 score | |||
| ≥ 2 | |||
| Sensitivity (95% CI) | 0.83 (0.36–0.99) | 0.50 (0.19–0.81) | 0.60 (0.26–0.88) |
| Specificity (95% CI) | 0.75 (0.67–0.82) | 0.74 (0.66–0.81) | 0.75 (0.67–0.82) |
| Positive LR (95% CI) | 3.33 (2.11–5.26) | 1.94 (0.98–3.84) | 2.40 (1.34–4.29) |
| ≥ 3 | |||
| Sensitivity (95% CI) | 0.83 (0.36–0.99) | 0.30 (0.07–0.65) | 0.20 (0.03–0.56) |
| Specificity (95% CI) | 0.90 (0.84–0.95) | 0.89 (0.82–0.93) | 0.88 (0.81–0.93) |
| Positive LR (95% CI) | 8.57 (4.64–15.80) | 2.63 (0.92–7.52) | 1.65 (0.44–6.15) |
| ≥ 4 | |||
| Sensitivity (95% CI) | 0.67 (0.22–0.96) | 0.20 (0.03–0.56) | 0.10 (0.03–0.45) |
| Specificity (95% CI) | 0.95 (0.90–0.98) | 0.94 (0.88–0.97) | 0.93 (0.87–0.97) |
| Positive LR (95% CI) | 13.7 (5.48–34.30) | 3.11 (0.78–12.50) | 1.40 (0.20–9.87) |