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Representative glomerular histology at 24 weeks of age from eNOS+/+m/m (control) mice, eNOS−/− m/m mice (eNOS−/−), eNOS+/+db/db (db/db) and eNOS−/−db/db (db/db eNOS−/−) mice. All mice are on the BKS background. Note the markedly increased mesangial expansion and glomerulosclerosis in the BKS eNOS−/−db/db mice.
