FIGURE 1.

Text mining analysis of the scientific literature to detect papers on the application of Zebrafish in Alzheimer’s disease research. The PubMed database was mined for zebrafish and Alzheimer’s disease using the search term, “zebrafish+alzheimer’s disease,” by the MedScan Reader 5 tool implemented in the Pathway Studio 9 Package (Nikitin et al., 2003b; Novichkova et al., 2003a). MedScan Reader 5 collects information and processes undertaken data using natural language processing (NLP). The language interprets these to logical concepts and extracts functional relationships between proteins, small molecules, and cellular processes (Nikitin et al., 2003b; Novichkova et al., 2003a). 119 publications were found. Abstracts of these publications were studied and review papers were removed such that 98 papers remained. (A) Venn diagram and (B) bar graph showing numbers of research papers in different areas. A concentration of research on Amyloidβ and Presenilin function is apparent.