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. Author manuscript; available in PMC: 2014 Jun 30.
Published in final edited form as: Pharm Res. 2012 Jul 14;29(9):2565–2577. doi: 10.1007/s11095-012-0787-4

Fig. 3.

Fig. 3

Effect of PLGA molecular weight (MW) on release of encapsulated tumor material. Proteins were released under controlled conditions from 5 mg of the three PLGA formulations; samples taken at designated time points and analyzed for protein content by the BCA assay. The initial burst of protein release was increased in association with the 80KDa PLGA (open square); p=0.008 versus 105KDa (open circle) and p=0.003 versus 45KDa (open triangle). Cumulative protein release over 8 days was maximal with 80KDa MW polymer; p =0.002 versus 105KDa and p =0.001 versus 45KDa. Data refers to mean ± SD of triplicates from a representative experiment.