. Author manuscript; available in PMC: 2014 Jun 30.

Published in final edited form as: Pharm Res. 2012 Jul 14;29(9):2565–2577. doi: 10.1007/s11095-012-0787-4

Table II.

Effect of PLGA MW on Encapsulation Profile. Extent and Efficiency of Encapsulation Increased with Increasing MW. Rotein Content in Lysate (μg)/Unit of Polymer (mg). Encapsulation Efficiency was Calculated as: (mass protein encapsulated ÷ mass protein used in encapsulation) × 100% formula: Mass Protein Encapsulated/mass Protein loaded) × 100%. Data represent mean and Standard Deviation of Pooled Observations from repeat Experiments and Values from a Representative Experiment

PLGA MW (KDa)	Protein content in lysate (μg)	Encapsulated protein (μg/mg of NP)	Encapsulation Efficiency (%)
45	3600±20181950	22±1512	24±9.530
80	3600±20181950	26±1715.6	33±15.540
105	3600±20181950	34±19.718	42±1746.2