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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Virology. 2014 May 14;0:172–182. doi: 10.1016/j.virol.2014.04.036

Figure 7.

Figure 7

Secreted NS1 diminishes the response to WNV VRP infection in vivo. C57BL/6 mice were pre-injected with purified sNS1 or sNS1-heat as described above and stimulated by injection of 1x105 iu WNV VRPs into each footpad. PLNs were collected and processed as described in Figure 6. IL-6 mRNA (A) and IFNβ mRNA (B) and WNV RNA levels (C) were analyzed by real-time qRT-PCR. A representative experiment out of three independent studies is shown.