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. 2014 Jun 6;18(3):433. doi: 10.1186/cc13910

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Copyright © 2014 Tamayo et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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IgM transcriptomic response in the presence/absence of sepsis. Left: comparison of immunoglobulin (Ig)M transcriptomic response between groups. HC, healthy control (n = 15); SIRS, systemic inflammatory response syndrome (n = 20); SEPSIS SOFA < =10, Sepsis with Sepsis-related Organ Failure Assessment score ≤10 (n = 39); SEPSIS SOFA >10, sepsis with SOFA score >10 (n = 16). Results for the ratio are expressed as (Copies IGHM/Copies CD20). Right: receiver operating characteristic curve of IGHM/CD20 predicting presence of sepsis in the comparison (sepsis versus SIRS). For this comparison septic patients were considered as a single group.