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. 2014 May 23;111(21):367–375. doi: 10.3238/arztebl.2014.0367

Table 1. Recommendations for emergency drug treatment in patients with anaphylaxis (adapted from Ring et al. [12]).

Drug substance Application route and dosage
Epinephrine Autoinjector for intramuscular administration, weight-adjusted:
   >10 kg 150 µg epinephrine
   >30 kg 300 µg epinephrine
Antihistamine Depending on patient age and preference, oral as a fluid or as (soluble) tablets; the permitted daily dose of any antihistamine can be recommended as a single dose. For dimetindene drops, similarly, a weight-adjusted dosage of the i.v. formulation can be recommended as dose to be taken orally
Corticosteroid Depending on patient age and preference, rectal or oral (as fluid or tablets) 50–100 mg prednisolone-equivalent dose
Optional β-mimetic, e.g., salbutamol In patients with known bronchial asthma: β2-sympathomimetic; in patients with expected obstruction of the airways: inhalational epinephrine preparation with spray head for drug vial (ask the pharmacist)

Note: An emergency kit for immediate treatment should include written instructions for using the medication (e.g., anaphylaxis card and/or anaphylaxis emergency plan)