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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Atherosclerosis. 2014 Apr 3;234(2):401–409. doi: 10.1016/j.atherosclerosis.2014.03.022

Figure 2.

Figure 2

Effects of diet on LpL, macrophages and inflammatory markers in proximal aorta in LDLR−/− mice. (A). Representative images of proximal artery sections stained for endothelial cells (EC), LpL and macrophages (MΦ) in LDLR−/− mice that were fed the specific diets for 12 weeks. “L” indicates lumen. (B). Immunofluorescence of aortic LpL (open bars) and macrophages (filled bars) quantitated for each group. Mean±SE, n=3–4. (C) mRNA analyses of arterial pro-inflammatory markers. Proximal aorta homogenates of LDLR−/− mice (n=5) were analyzed for mRNA of CD68, VCAM-1, IL-6 and TLR-4 in each group. Data are expressed as mean±SE. *, SAT vs. chow; **, vs. SAT, p<0.05.