Table 1.

Plasma and aortic fatty acid composition in LDLR−/− mice (weight % of total fatty acids).

	Chow		SAT		S:n-3 3:1		S:n-3 1:1		n-3
	plasma	aorta	plasma	aorta	plasma	aorta	plasma	aorta	plasma	aorta
12:0	0.00±0.00	0.00±1.23^a	1.21±0.19	7.65±1.23^b	0.23±0.16	6.06±0.91^bc	0.00±0.00	5.08±0.00^c	0.00±0.00	0.00±0.00^a
14:0	0.00±0.00	2.13±0.19^a	2.68±0.16	9.09±0.63^b	0.89±0.f35	8.30±0.26^b	1.31±0.18	8.01±0.53^b	0.42±0.26	4.06±1.08^c
16:0	20.44±0.29	26.71±0.97^a	20.87±1.17	18.40±0.97^b	21.95±1.47	19.99±2.53^b	21.87±2.04	22.00±1.49^ab	23.75±0.58	20.45±2.76^b
16:1	3.19±0.24	8.41±0.67	8.19±0.47^*	4.86±1.33 ^b	7.95±0.93^*	4.44±1.43^b	5.80±0.50	4.48±0.69^b	5.01±0.17	4.56±1.36^b
18:0	7.93±0.07	6.37±0.36^ac	7.89±0.21	4.03±0.79^b	9.65±0.58	5.51±0.58^ab	11.20±0.84	7.20±0.50^c	9.81±0.28	9.73±0.07^d
18:1 (n-9)	12.78±0.37	38.50±2.14^a	23.75±0.4^*	30.93±2.31^b	18.72±1.54^*^¥	27.35±0.37^bc	13.90±0.35^#^¥	24.25±1.04^c	8.70±0.44^*^#	18.19±1.86^d
18:2 (n-6)	36.44±0.58	13.28±1.18^ac	20.74.±0.73^*	19.93±1.66^b	20.95±0.63^*^¥	19.96±2.43^b	15.83±0.82^*^#^¥	17.12±1.04^ab	11.71±0.38^*^#	11.57±1.17^c
18:3 (n-3)	0.93±0.03	0.71±0.09	0.46±0.02	0.87±0.60	0.00±0.00	1.09±0.55	0.26±0.26	1.69±0.18	0.00±0.00	1.60±0.92
20:3 (n-3)	1.12±0.07	0.28±0.25^a	1.28±0.35	0.52±0.10^ab	0.28±0.17	0.39±00.06^a	0.10±0.15	0.40±0.01^a	0.42±0.27	0.89±0.06^b
20:4 (n-6)	9.13±0.19	2.49±0.77^ad	10.49±0.72	2.47±0.68^ad	4.57±1.16^*^#^¥	0.97±0.15^bc	6.96±0.67^#^¥	1.03±0.04^c	10.92±0.31	3.14±0.05^d
20:5 (n-3)	2.73±0.08	0.00±0.00^a	1.14±1.14	0.00±0.00^a	9.12±2.55^#^¥	0.96±0.08^ab	14.38±1.41^*^#	1.27±0.22^b	16.84±0.31^*^#	3.51±0.74^c
22:4 (n-6)	0.00±0.00	0.00±0.00	0.00±0.00	0.33±0.08	0.00±0.00	0.20±0.07	0.00±0.00	0.09±0.08	0.00±0.00	0.34±0.58
22:5 (n-3)	0.00±0.00	0.12±0.12^a	0.00±0.00	0.14±0.04^ab	0.22±0.22	1.11±0.25^ab	0.00±0.00^#	1.51±0.31^b	0.37±0.23	3.91±0.65^c
22:6 (n-3)	5.42±0.20	0.99±0.33^a	1.31±0.12^*	0.77±0.33^a	5.50±1.51^#^¥	3.68±0.70^ab	8.35±0.71^#^¥	5.87±0.48^b	12.35±0.40^*^#	18.05±2.25^c

At the end of feeding period, mouse plasma (n=5) and aorta (n=3) from each group were analyzed for fatty acid composition using GLC as described in Methods. Results are expressed as mean weight percent ±SE. Different superscripts are significantly different, p<0.05.

vs. chow;

vs. SAT;

^¥

vs. n-3, p<0.05.