Table 1. Summary of data indicating the broad ligand specificity of products of the Arabidopsis GLR gene family.
GLR gene | Assay system | Agonist(s) | Non-agonist(s) | Reference |
---|---|---|---|---|
AtGLR1.4 | Xenopus oocytes/ patch clamp |
Met, Trp, Phe, Leu, Tyr, Asn, Thr | Other proteinogenic amino acids | [9] |
AtGLR1.4 | Knockout mutant/ cotyledons/ membrane potential measurements |
Met | L-Glu | [9] |
AtGLR3.3 | Knockout mutant/roots/ membrane potential measurements |
GSH, L-Ala, Asn, Cys, L-Glu, Gly, L-Ser | Other proteinogenic amino acids, D-Glu, D-Ser, D-Ala, GABA, NMDA | [6] |
AtGLR3.3/AtGLR3.4 | Knockout mutants/ hypocotyls/ membrane potential measurements |
L-Glu, L-Ala, Asn, Cys, Gly, L-Ser | Other proteinogenic amino acids | [7] |
AtGLR3.4 | HEK293 cells/ patch clamp |
Asn, L-Ser, Gly | L-Glu, L-Ala, Cys, Phe | [10] |
GABA, gamma-aminobutyric acid; GLR, glutamate-like receptor; GSH, glutathione (reduced); NMDA, N-methyl D-aspartate.