Table 2. Summary of data supporting a role for Arabidopsis GLR genes in the defense response.
| Gene(s) | Manipulation | Effect on disease resistance |
Other effects on the defense response |
Reference |
|---|---|---|---|---|
| RsGluR | Constitutive overexpression in Arabidopsis (35S promoter) | Increased basal resistance to Botrytis cinerea | Increased expression of defense-related genes (e.g. defensins, jasmonic acid biosynthetic genes) | [14] |
| AtGLR3.3 | Knockout mutant | Increased susceptibility to Pseudomonas syringae | Attenuation of P. syringae- elicited induction of defence-related genes Loss of ability of GSH pre-treatment to confer resistance to P. syringae |
[17] |
| AtGLR3.3 | Knockout mutant | Increased susceptibility to Hyaloperonospora arabidopsidis; No effect on susceptibility to B. cinerea |
Attenuation of oligogalacturonide-elicited increase in reactive oxygen species (ROS) and nitric oxide (NO) production; Attenuation of oligogalacturonide-elicited and H. arabidopsidis-elicited effects on defence gene expression |
[18] |
| AtGLR3.3, AtGLR3.4, AtGLR3.6 | Knockout mutants | Not tested | Attenuation of wound- induced surface potential changes; Attenuation of long-distance wound-stimulated expression of JAZ (jasmonate-signalling) genes |
[20] |
GSH, glutathione (reduced).