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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Drug Alcohol Depend. 2014 Apr 28;140:25–32. doi: 10.1016/j.drugalcdep.2014.04.020

Fig. 2.

Fig. 2

Effects of adolescent methylphenidate treatment during extinction training. (a) Number of sessions to reach extinction criterion; (b) Active lever responding averaged across the last three sessions of extinction and expressed as the percentage of the self-administration maintenance baseline. Experiments were conducted in adult Wistar-Kyoto (WKY), Wistar (WIS), and Spontaneously Hypertensive (SHR) rats after adolescent methylphenidate (MPH) or vehicle (VEH) treatment was discontinued (n = 7–10 per strain and treatment). Values are presented as mean ± SEM. # p ≤ 0.01 compared to SHR (main effect of strain).