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. Author manuscript; available in PMC: 2014 Jun 30.
Published in final edited form as: Cell Stem Cell. 2010 Mar 5;6(3):238–250. doi: 10.1016/j.stem.2010.01.004

Figure 4. MGE Cell Transplantation Ameliorates the Behavioral Deficits of 6-OHDA Lesions.

Figure 4

(A) Rotation test. 6-OHDA-lesioned rats that received MGE cell transplantation (n = 18) performed fewer contralateral rotations under apomorphine stimulation than nontransplanted 6-OHDA controls (n = 15), 6-OHDA-lesioned rats that received sham injection (n = 11), or dead MGE cells (n = 10). ANOVA showed that the difference between groups was significant at 9, 11, and 14 weeks (asterisks). Postcomparison analysis showed that the MGE group rotated significantly less than the 6-OHDA-treated control groups at 9, 11, and 14 weeks. Error bars depict standard error of the mean.

(B) Length of stride test. 6-OHDA-lesioned rats that received MGE cell transplantation (n = 18) had a longer stride than did nontransplanted 6-OHDA controls (n = 15) and 6-OHDA-lesioned rats that received sham injection (n = 11). Naive rats (n = 10) are included for comparison. ANOVA showed that the difference between groups was significant at 11 weeks. Postcomparison analysis showed that the MGE group had a significantly longer stride than the 6-OHDA-lesioned control groups at 11 weeks (asterisk). See also Figure S1.