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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Transl Res. 2013 Apr 6;162(1):45–55. doi: 10.1016/j.trsl.2013.03.005

Figure 5. Effects of p38 MAPK and Rho pathway inhibition on LTA/PepG-induced inflammatory signaling.

Figure 5

Figure 5

HPAEC (A) or HLMVEC (B) were pretreated with SB203580 (20 μM) or Y27632 (2 μM) for 30 min followed by LTA/PepG stimulation for 4 hours. Activation of Rho cascade, p38 MAPK, and NFκB cascades was examined by analysis of specific protein phosphorylation and IκBα degradation. Equal protein loading was confirmed by probing of membranes with β-tubulin antibodies. C – Quantitative analysis of western blot data. Results of densitometry are shown as mean ± SD, * p<0.05; n=6 experiments.