Table 2.

MRI studies of structural brain networks in typical development

Study	Subjects	Connectivity measure	Parcellation	Network changes with age
Hagmann et al32	30 subjects: 18 months to 18 years	DTI and q-ball	66 or 241 nodes, landmark-based	Global efficiency ↑, clustering ↓, small-worldness ↓
Fan et al33	28 subjects: 1 month, 1 year, 2 years longit. + 27 adults	Grey matter volume correlation	90 nodes, AAL34	Global efficiency ↑, modularity ↑ from 1 to 2 years
Yap et al35	39 subjects: 2 weeks, 1 year, 2 years longit.	DTI	78 nodes, AAL34	Global efficiency constant, local efficiency ↑
Dennis et al36	102 subjects: 12 years, 16 years + 337 adults	HARDI	70 nodes, gyral-based	Global efficiency ↑, clustering ↓, small-worldness ↓, modularity ↓
Huang et al37	25 neonates, 13 toddlers, 25 pre-adolescents + 18 adults	DTI, probabilistic tracking	80 nodes, AAL,34 adult ICBM-152 template38	Global efficiency ↑, clustering ↓, small-worldness ↓
Khundrakpam et al39	203 subjects: 5–8, 8–11, 11–15 and 15–18 years	Cortical thickness covariance	78 nodes, AAL34	Local efficiency ↓, modularity ↓, global efficiency ↑ in late childhood
Tymofiyeva et al40	26 subjects: pre-term, term 1–14 days, 6 months + 7 adults	DTI	100 nodes, template-free equal-area sphere partitioning	Global efficiency ↑, clustering ↓, modularity ↓, small-worldness ↓ (except pre-term)

AAL, anatomical automatic labelling atlas; DTI, diffusion tensor imaging; ICBM, International Consortium for Brain Mapping; HARDI, high angular resolution diffusion imaging; longit., longitudinal.