Figure 2.

Effects of the MPBL on latency to hot plate test. Values are mean±SEM, (n=5); *p<0.05 as compared with vehicle control (one-way ANOVA followed by Dunnett’s test). Group I animals received vehicle (1% Tween 80 in water), Group II received nalbuphine 10 mg/kg body weight, Group III and Group IV were treated with 100 and 200 mg/kg body weight (p.o.) of the crude extract of P. betle, respectively