Table 3.
Effect of essential oil in DTH response using SRBCs as an antigen in mice, 7-days treatment
|
Groups/dose
mg/kg |
DTH response, mean paw edema in mm
|
||||
|---|---|---|---|---|---|
| Geraniol | Geranial acetate | Gingerol | Eugenol | ||
| I – Control | 0.2±0.03 | 0.2±0.02 | 0.2±0.118 | 0.25±0.02 | |
| II – 50 | 3.9±0.3 | 2.8±0.23 | 3.2±0.3 | 2.2±0.2 | |
| III – 100 | 4.3±0.4 | 2.9±0.3 | 3.0±0.4 | 2.4±0.2 | |
| IV – 200 | 4.4±0.4 | 5.1±0.7 | 3.5±0.5 | 3.6±0.5 | |
| V- 400 | 5.1±0.6 | 5.2±0.8 | 3.3±0.4 | 3.8±0.5 | |
| VI – 800 | 5.6±0.7 | 5.9±0.8 | 3.5±0.5 | 4.4±0.6 | |
| ANOVA | F | 1.518 | 2.086 | 1.230 | 2.011 |
| df | 5,20 | 5,20 | 5,20 | 5,20 | |
| P | <0.05 | <0.05 | <0.05 | <0.05 | |
Values are mean±SEM, n=6 in each group, *p<0.05 when compared with respective control group (Dunnett’s test).