Table 4.
Effect of essential oil in DTH response using SRBCs as an antigen in mice, 15-days treatment
|
Groups/dose
mg/kg |
DTH response-mean paw edema in mm
|
||||
|---|---|---|---|---|---|
| Geraniol | Geranial acetate | Gingerol | Eugenol | ||
| I – Control | 0.2±0.03 | 0.2±0.03 | 0.2±0.118 | 0.25±0.02 | |
| II – 50 | 5.0±0.3 | 4.0±0.2 | 3.0±0.4 | 4.9±0.3 | |
| III – 100 | 5.0±0.5 | 4.1±0.4 | 5.9±0.9 | 5.0±0.5 | |
| IV – 200 | 5.2±0.6 | 4.3±0.6 | 5.9±0.9 | 5.2±0.5 | |
| V- 400 | 5.9±0.8 | 5.6±0.8 | 6.2±1.01 | 5.3±0.6 | |
| VI – 800 | 6.2±0.9 | 5.7±0.8 | 6.3±1.0212 | 5.9±0.8 | |
| ANOVA | F | 1.361 | 1.648 | 1.560 | 1.286 |
| df | 5,20 | 5,20 | 5,20 | 5,20 | |
| P | <0.05 | <0.05 | <0.05 | <0.05 | |
Values are mean±SEM, n=6 in each group, *p<0.05 when compared with respective control group (Dunnett’s test).