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AZA had no analgesia in thermal-stimulated acute pain, but attenuated chemical-stimulated acute pain. (A) mouse tail-flick test (n=9–10), (B) mouse hot-plate test (n=9–10). The basal responses of mice to thermal stimuli were tested before drug administration. (C) mouse capsaicin test (n=10), (D) mouse formalin test (n=8–10), (E) mouse acetic acid-induced writhing test (n=10). (A) and (B), no statistical significant difference was obtained. (C), (D), and (E), cP<0.01 vs control.
