Table 3. Mean scores (and standard deviations) on the 30-item European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire, the Functional Assessment of Cancer Therapy-Lung, and the Medical Outcomes Study 36-item Short-form Health Survey for the 50 lung cancer patients studied.
| Questionnaire | Total | Subgroup | p | |||
| Symptom severity | ||||||
| Mild | Moderate | Severe | ||||
| EORTC QLQ-C30 | ||||||
| Global health status | 70.83 (25.6) | 75.8 (26.3) | 65.5 (19.2) | 58.3 (32.5) | NS | |
| Physical functioning | 70.13 (27.7) | 77.3 (22.5) | 72.8 (17.4) | 27.8 (35.9) | < 0.001 | |
| Role functioning | 70.33 (32.3) | 78.9 (30.3) | 70.2 (18.7) | 27.8 (37.5) | 0.001 | |
| Emotional functioning | 69.67 (23.7) | 77.2 (21.4) | 61.9 (16.6) | 50.0 (33.7) | 0.010 | |
| Cognitive functioning | 79.00 (23.7) | 83.3 (23.6) | 76.2 (20.4) | 63.9 (28.7) | NS | |
| Social functioning | 82.33 (31.1) | 85.6 (27.6) | 89.3 (24.9) | 50.0 (44.7) | 0.020 | |
| FACT-L | ||||||
| Physical well-being | 21.66 (6.1) | 22.8 (5.9) | 22.3 (4.2) | 14.7 (6.7) | 0.009 | |
| Social/family well-being | 19.78 (5.7) | 20.7 (5.4) | 18.4 (6.5) | 18.5 (4.7) | NS | |
| Emotional well-being | 18.44 (4.6) | 18.5 (5.4) | 18.1 (3.3) | 18.8 (3.3) | NS | |
| Functional well-being | 16.64 (7.2) | 18.9 (7.6) | 14.4 (4.6) | 10.5 (5.9) | 0.010 | |
| FACT-G | 76.52 (18.0) | 80.9 (19.6) | 73.1 (12.6) | 62.5 (12.9) | 0.049 | |
| FACT-L | 95.80 (21.7) | 101.6 (22.7) | 92.7 (14.9) | 74.0 (15.9) | 0.010 | |
| FACT-L TOI | 57.58 (16.3) | 62.4 (15.9) | 56.2 (9.5) | 36.7 (5.9) | 0.001 | |
| SF-36 | ||||||
| Physical functioning | 61.7 (30.4) | 68.5 (28.6) | 62.9 (23.2) | 25.0 (31.9) | 0.004 | |
| Role-physical | 40.5 (42.5) | 51.7 (44.5) | 28.6 (37.6) | 12.5 (20.9) | NS | |
| General health | 64.7 (23.1) | 67.7 (24.8) | 61.6 (16.2) | 56.8 (28.9) | NS | |
| Vitality | 60.0 (29.1) | 68.7 (26.7) | 54.3 (22.9) | 30.0 (29.1) | 0.006 | |
| Social functioning | 67.8 (31.9) | 78.3 (27.1) | 58.1 (30.1) | 37.5 (37.1) | 0.005 | |
| Role-emotional | 49.3 (45.3) | 63.3 (44.9) | 28.6 (38.9) | 27.8 (38.9) | 0.024 | |
| Mental health | 66.6 (21.4) | 71.9 (21.3) | 62.3 (15.5) | 50.0 (26.1) | 0.047 | |
| Total | 59.7 (24.5) | 68.1 (24.5) | 52.1 (17.1) | 35.1 (17.7) | 0.003 |
EORTC QLQ-C30: : European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire;
FACT-L: : Functional Assessment of Cancer Therapy-Lung;
FACT-G: : Functional Assessment of Cancer Therapy-General;
TOI
: Trial Outcome Index;
SF-36: : Medical Outcomes Study 36-item Short-Form Health Survey;
NS
: not significant.
ANOVA (with post hoc Bonferroni correction) revealed significant differences between the patients with severe symptoms and those with mild or moderate symptoms.