Table 1. Lung volume recruitment and pulmonary function during admissions due to asthma exacerbation.
Variables, 1991-2009 | 1991 | 1994 | 2006 | 2008 | April 1, 2009 | ||
(3 mo. after the start of NIV) | (1.5 mo. before the incident) | ||||||
Pulmonary function | |||||||
VC, L (%) | 1.00 (37) | 1.32 (49) | 1.2 (51) | ||||
FEV1, L (%) | 0.70 (30) | 0.92 (41) | 0.6 (34) | ||||
Albuterol | 0.80 (34) | 0.7 (38) | |||||
FEV1/VC, % | 70 | 70 | 51 | ||||
Albuterol, % | 78 | 58 | |||||
TLC, L (%) | 3.00 (65) | 3.38 (74) | 3.47 (77) | ||||
ITGV, L (%) | 2.30 (90) | 2.53 (99) | |||||
Raw, kPa.L-1.s (n) | 0.56 (0.3) | 0.57 (0.3) | |||||
Blood gas analysis | arterial | arterial | capillary | capillary | capillary | ||
pH | 7.37 | 7.39 | 7.40 | 7.42 | 7.44 | ||
PCO2, mmHg | 52 | 48.0 | 45 | 44 | 51 | ||
Bic, mmol/L | 31 | 30 | 27.9 | 28.0 | 31.6 | ||
PO2, mmHg | 52 | 61 | 61 | 61 | 59 | ||
SO2, % | 85 | 90 | 91 | 91 | 90 | ||
SpO2, % | 95 | 94 | 93 | ||||
Variables, 2004-2009LVR-related measurements | 2004 | 2005 | 2006 | 2007 | 2009 | ||
(prior to the start of AS) | (3 mo. after the start of AS) | ||||||
PCF unassisted, L/s | 2.20 | 2.25 | 2.50 | 3.08 | 2.83 | -- | |
PCF after MIC, L/s | 2.75 | 3.50 | 4.08 | 4.00 | -- | ||
RR, min-1 | 16 | 18 | 22 | 16 | 20-24 |
: months
: noninvasive ventilation; incident: acquisition of pneumothorax
: intrathoracic gas volume
: airway resistance
: bicarbonate
: carbon dioxide tension
: oxygen tension
: oxygen saturation
: lung volume recruitment
: peak cough flow
: maximum insufflation capacity