Table 4. Significantly different categorical variables in the groups studied.^* .

Group	Variable	Categorization		p	OR	95% CI	Variable	Categorization		p	OR	95% CI
	Age	≤ 154 mo	> 154 mo				Age at first clinical manifestations	≤ 3 mo	> 3 mo
G0		18	46	< 0.001	0.238	0.121-0.457		19	37	< 0.001	0.239	0.119-0.47
G1		36	31		1.202	0.654-2.217		48	18		2.974	1.539-5.884
G2		37	11		4.754	2.263-10.53		30	18		1.366	0.689-2.749
	Age at diagnosis	≤ 24 mo	> 24 mo				Age at digestive disease	≤ 3 mo	>3 mo
G0		15	44	< 0.001	0.157	0.007-0.315		13	27	0.023	0.362	0.165-0.77
G1		41	23		1.95	1.034-3.725		37	25		1.852	0.958-3.615
G2		36	12		3.563	1.715-7.74		26	22		1.227	0.615-2.464
	Age at pulmonary disease	≤ 6 mo	> 6 mo				PI	Presence	Absence
G0		20	32	0.006	0.385	0.179-0.704		35	29	< 0.001	0.08	0.03-0.192
G1		44	21		2.258	1.181-4.391		62	5		4.71	1.817-14.35
G2		28	20		1.158	0.586-2.312		46	2		7.007	2.136-51.37
	MI	Presence	Absence				Age at first PA isolate	≤ 3 mo	> 3 mo
G0		5	60	0.047	0.335	0.108-0.892		9	26	0.001	0.229	0.093-0.535
G1		13	54		1.569	0.683-3.576		30	25		1.263	0.627-2.552
G2		10	38		1.662	0.682-3.906		28	13		2.794	1.29-6.248
	MPA	Presence	Absence				NMPA	Presence	Absence
G0		21	44	0.068	0.553	0.2731-0.984		28	37	0.025	0.438	0.233-0.814
G1		35	32		1.914	1.034-3.56		41	26		1.39	0.752-2.593
G2		20	28		0.97	0.491-1.898		32	16		1.82	0.916-3.702
	BC	Presence	Absence
G0		4	61	0.101	0.313	0.088-0.91
G1		12	55		1.83	0.757-4.426
G2		8	40		1.447	0.548-3.618

^mo: months

^G0: absent F508del

^G1: heterozygous F508del patients

^G2: homozygous F508del patients

^MI: meconium ileus

^PA: Pseudomonas aeruginosa

^MPA: mucoid PA colonization

^BC. Burkholderia cepacia colonization

^PI: pancreatic insufficiency

^PA: P. aeruginosa

^NMPA: non-mucoid PA colonization.

^*Chi-square test