Table 1.
Patient Demographics and Clinicopathologic Characteristics for T1a,bN0 Patients With Breast Cancer, NCCN 2000-2009
| Characteristic | T1aN0 Patients With Breast Cancer |
T1bN0 Patients With Breast Cancer |
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|---|---|---|---|---|---|---|---|---|
| No Chemotherapy or Trastuzumab (n = 1,197) |
Chemotherapy With or Without Trastuzumab (n = 102) |
No Chemotherapy or Trastuzumab (n = 2,205) |
Chemotherapy With or Without Trastuzumab (n = 609) |
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| No. | % | No. | % | No. | % | No. | % | |
| Age, years | ||||||||
| < 50 | 325 | 27 | 60 | 59 | 437 | 20 | 278 | 46 |
| 50-60 | 394 | 33 | 28 | 27 | 651 | 30 | 211 | 35 |
| 60-70 | 296 | 25 | 12 | 12 | 614 | 28 | 105 | 17 |
| ≥ 70 | 182 | 15 | 2 | 2 | 503 | 23 | 15 | 2 |
| Method of detection | ||||||||
| Abnormal screening mammogram | 957 | 80 | 57 | 56 | 1,705 | 77 | 349 | 57 |
| Symptoms | 177 | 15 | 36 | 35 | 423 | 19 | 230 | 38 |
| Other/unknown | 63 | 5 | 9 | 9 | 77 | 3 | 30 | 5 |
| Race/ethnicity | ||||||||
| Non-Hispanic white | 1,012 | 85 | 72 | 71 | 1,908 | 87 | 501 | 82 |
| Non-Hispanic black | 71 | 6 | 12 | 12 | 97 | 4 | 31 | 5 |
| Hispanic | 48 | 4 | 9 | 9 | 106 | 5 | 39 | 6 |
| Asian-Pacific Islander | 42 | 4 | 7 | 7 | 63 | 3 | 23 | 4 |
| American Indian | 2 | < 1 | 1 | 1 | 4 | < 1 | 2 | < 1 |
| Unknown | 14 | 1 | 1 | 1 | 19 | 1 | 8 | 1 |
| Other | 8 | 1 | 0 | 0 | 8 | 0 | 5 | 1 |
| Comorbidity score* | ||||||||
| 0 | 910 | 76 | 94 | 92 | 1,550 | 70 | 503 | 83 |
| 1 | 159 | 13 | 5 | 5 | 388 | 18 | 66 | 11 |
| ≥ 2 | 128 | 11 | 3 | 3 | 267 | 12 | 40 | 6 |
| Year of diagnosis | ||||||||
| 2000 | 82 | 7 | 2 | 2 | 134 | 6 | 37 | 6 |
| 2001 | 76 | 6 | 5 | 5 | 175 | 8 | 46 | 8 |
| 2002 | 103 | 9 | 6 | 6 | 175 | 8 | 35 | 6 |
| 2003 | 92 | 8 | 7 | 7 | 213 | 10 | 59 | 10 |
| 2004 | 115 | 10 | 3 | 3 | 233 | 11 | 59 | 10 |
| 2005 | 146 | 12 | 16 | 16 | 269 | 12 | 67 | 11 |
| 2006 | 145 | 12 | 15 | 15 | 249 | 11 | 80 | 13 |
| 2007 | 140 | 12 | 14 | 14 | 228 | 10 | 74 | 12 |
| 2008 | 172 | 14 | 14 | 14 | 287 | 13 | 81 | 13 |
| 2009 | 126 | 11 | 20 | 20 | 242 | 11 | 71 | 12 |
| Histology | ||||||||
| Ductal | 954 | 80 | 95 | 93 | 1,726 | 78 | 549 | 90 |
| Lobular | 100 | 8 | 2 | 2 | 153 | 7 | 24 | 4 |
| Mixed | 52 | 4 | 1 | 1 | 130 | 6 | 22 | 4 |
| Other | 91 | 8 | 4 | 4 | 196 | 9 | 14 | 2 |
| Subtype | ||||||||
| HR-positive, HER2-negative | 972 | 81 | 12 | 12 | 2,005 | 91 | 241 | 40 |
| HR-positive, HER2-positive | 102 | 9 | 33 | 32 | 89 | 4 | 110 | 18 |
| HR-negative, HER2-positive | 49 | 4 | 32 | 31 | 17 | 1 | 88 | 14 |
| HR-negative, HER2-negative | 74 | 6 | 25 | 25 | 94 | 4 | 170 | 28 |
| Grade | ||||||||
| Low-intermediate | 876 | 73 | 28 | 27 | 1,789 | 81 | 245 | 40 |
| High | 270 | 23 | 72 | 71 | 391 | 18 | 355 | 58 |
| Unknown | 51 | 4 | 2 | 2 | 25 | 1 | 9 | 1 |
| Lymphovascular invasion | ||||||||
| Yes | 41 | 3 | 11 | 11 | 115 | 5 | 97 | 16 |
| No | 1,132 | 95 | 89 | 87 | 2,047 | 93 | 506 | 83 |
| Unknown | 24 | 2 | 2 | 2 | 43 | 2 | 6 | 1 |