Table A3.
Treatment Characteristic | T1aN0 Breast Cancer |
T1bN0 Breast Cancer |
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HR-Positive/HER2-Negative (n = 984) |
HR-Positive/HER2-Positive (n = 135) |
HR-Negative/HER2-Positive (n = 81) |
HR-Negative/HER2-Negative (n = 99) |
HR-Positive/HER2-Negative (n = 2,246) |
HR-Positive/HER2-Positive (n = 199) |
HR-Negative/HER2-Positive (n = 105) |
HR-Negative/HER2-Negative (n = 264) |
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No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | No. | % | |
Definitive surgery | ||||||||||||||||
Mastectomy | 284 | 29 | 59 | 44 | 52 | 64 | 39 | 39 | 501 | 22 | 57 | 29 | 45 | 43 | 63 | 24 |
Breast-conserving surgery | 699 | 71 | 76 | 56 | 29 | 36 | 60 | 61 | 1,745 | 78 | 142 | 71 | 60 | 57 | 201 | 76 |
No definitive surgery | 1 | < 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiation therapy | ||||||||||||||||
No | 330 | 34 | 62 | 46 | 52 | 64 | 40 | 40 | 644 | 29 | 69 | 35 | 45 | 43 | 67 | 25 |
Yes | 654 | 66 | 73 | 54 | 29 | 36 | 59 | 60 | 1,602 | 71 | 130 | 65 | 60 | 57 | 197 | 75 |
Hormone therapy | ||||||||||||||||
No | 192 | 20 | 31 | 23 | 75 | 93 | 92 | 93 | 226 | 10 | 20 | 10 | 101 | 96 | 253 | 96 |
Yes | 792 | 80 | 104 | 77 | 6 | 7 | 7 | 7 | 2,020 | 90 | 179 | 90- | 4 | 4 | 11 | 4 |
Trastuzumab | ||||||||||||||||
No | 984 | 100 | 110 | 81 | 60 | 74 | 98 | 99 | 2,239 | 100 | 127 | 64 | 57 | 54 | 259 | 98 |
Yes | 0 | 0 | 25 | 19 | 21 | 26 | 1 | 1 | 7 | < 1 | 72 | 36 | 48 | 46 | 5 | 2 |
Chemotherapy | ||||||||||||||||
No | 972 | 99 | 103 | 76 | 50 | 62 | 75 | 76 | 2,005 | 89 | 92 | 46 | 17 | 16 | 94 | 36 |
Yes | 12 | 1 | 32 | 24 | 31 | 38 | 24 | 24 | 241 | 11 | 107 | 54 | 88 | 84 | 170 | 64 |
Type of chemotherapy | ||||||||||||||||
Anthracycline-containing regimen | 7 | 58 | 9 | 28 | 13 | 42 | 14 | 58 | 144 | 60 | 40 | 37 | 36 | 41 | 98 | 58 |
CMF-containing regimen | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11 | 5 | 2 | 2 | 2 | 2 | 8 | 5 |
Taxane-containing regimen | 4 | 33 | 13 | 41 | 10 | 32 | 1 | 4 | 40 | 17 | 25 | 23 | 18 | 20 | 26 | 15 |
Anthracycline-containing regimen-taxane | 0 | 0 | 4 | 13 | 4 | 13 | 7 | 29 | 39 | 16 | 23 | 21 | 23 | 26 | 34 | 20 |
Single chemotherapy agent | 1 | 8 | 6 | 19 | 4 | 13 | 2 | 8 | 6 | 2 | 17 | 16 | 9 | 10 | 4 | 2 |
Other | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | < 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Abbreviations: CMF, cyclophosphamide, methotrexate, fluorouracil; HER2, human epidermal growth factor receptor 2; HR, hormone receptor; NCCN, National Comprehensive Cancer Network.