Fig. 2.

The percentage and frequency of select B-cell subsets is differentially enhanced with EPA and DHA. Spleen weight (A) and number of splenocytes (B) and B cells from mice fed control, HF, HF-OA, HF-EPA, and HF-DHA diets for 5 weeks. Corresponding percentage (C) and frequency (D) of IgM⁺IgD⁻CD21^lowCD23⁻, IgM⁺IgD⁺CD21^midCD23⁺, IgM⁺IgD⁺CD21^hiCD23⁺, IgM⁺IgD⁻CD21^hiCD23⁻, and IgD⁺IgM⁻CD21^midCD23⁺ B-cell subsets at 5 weeks. Spleen weight (E) and number of splenocytes (F) and B cells and corresponding percentage (G) and frequency (H) of B-cell subsets from mice fed various diets for 10 weeks. Data are average ± SE from eight animals per diet. Asterisks indicate significance from control unless indicated by a bracket: *P < 0.05, **P < 0.01, ***P < 0.001.