Fig. 3.

Surface IgM and CD23 expression are differentially enhanced with EPA and DHA. Splenic B220⁺ B cells were isolated from mice consuming a control, HF, HF-OA, HF-EPA, or HF-DHA diet for 5 weeks or 10 weeks. Surface expression of IgM, IgD, CD23, and CD21 at 5 (A) and 10 weeks (B) were measured via flow cytometry. Data are average ± SE from seven to eight animals per diet. Asterisks indicate significance from control: *P < 0.05, ***P < 0.001.