TABLE 1.
Characteristics and clinical measures of the study participants by menopausal status
| Total (N = 120) | Pre-/Early Peri (N = 52) | Late Peri/Post (N = 68) | P | |
| Age, years | 50.4 (1.9) | 50.0 (1.6) | 50.6 (2.1) | 0.11 |
| Black, n (%) | 51 (42.5) | 24 (46.2) | 27 (39.7) | 0.48 |
| Smoker, n (%) | 21 (17.7) | 8 (15.7) | 13 (19.1) | 0.63 |
| Alcohol consumption, n (%) | 0.20 | |||
| None | 71 (60.2) | 33 (66.0) | 38 (55.9) | |
| >2 servings/week | 21 (17.8) | 10 (20.0) | 11 (16.2) | |
| ≤2 servings/week | 26 (22.0) | 7 (14.0) | 19 (27.9) | |
| BMI, kg/m2 | 30.2 (7.5) | 29.7 (7.5) | 30.6 (7.6) | 0.53 |
| Physical activity | 7.8 (1.7) | 8.1 (1.5) | 7.6 (1.8) | 0.12 |
| HDL-C, mg/dla | 56.6 (14.9) | 56.7 (16.2) | 56.5 (14.1) | 0.94 |
| LDL-C, mg/dla | 124.9 (38.7) | 113.0 (33.3) | 133.7 (40.3) | 0.009 |
| ApoA, mg/dla | 165.0 (26.7) | 162.1 (27.7) | 167.2 (26.0) | 0.36 |
| ApoB, mg/dla | 114.0 (33.9) | 104.0 (27.2) | 121.5 (36.7) | 0.01 |
| Triglycerides, mg/dla | 107.0 (80.0,158.0) | 100.5 (77.0, 146.0) | 111.5 (80.0, 186.0) | 0.35 |
| VLDL-P concentration, nmol/l | ||||
| Total | 78.6 (38.2) | 69.4 (28.1) | 85.7 (43.2) | 0.01 |
| Large | 1.4 (0.3, 4.2) | 1.1 (0.3, 2.7) | 1.6 (0.3, 5.9) | 0.14 |
| Medium | 19.5 (8.9, 34.8) | 15.6 (7.8, 28.0) | 21.7 (10.0, 43.4) | 0.08 |
| Small | 49.9 (20.7) | 46.6 (15.6) | 52.4 (23.6) | 0.11 |
| LDL-P concentration, nmol/l | ||||
| Total | 1,180.6 (1,026.6, 1,420.9) | 1,154.2 (955.6, 1,297.9) | 1,231.9 (1,053.5, 1,458.5) | 0.006 |
| Large | 604.0 (478.0, 795.2) | 606.4 (480.8, 774.0) | 602.2 (476.0, 846.6) | 0.71 |
| Small (total) | 476.1 (291.3, 708.7) | 428.7 (291.3, 629.7) | 532.5 (290.6, 761.6) | 0.25 |
| Medium small | 90.8 (61.8, 134.2) | 86.8 (61.2, 124.4) | 108.0 (62.7, 147.0) | 0.23 |
| Very small | 373.3 (223.9, 570.5) | 354.9 (223.9, 517.7) | 408.8 (225.0, 599.8) | 0.32 |
| HDL-P concentration, umol/l | ||||
| Total | 32.7 (6.9) | 31.9 (6.6) | 33.3 (7.1) | 0.25 |
| Large | 6.8 (3.1) | 6.9 (2.7) | 6.7 (3.4) | 0.64 |
| Medium | 1.5 (0.3, 4.8) | 1.7 (0.6, 4.5) | 1.3 (0, 5.6) | 0.47 |
| Small | 22.9 (6.0) | 22.0 (0.6) | 23.7 (5.4) | 0.11 |
| VLDL-P size, nm | 48.1 (9.3) | 48.2 (9.8) | 48.0 (9.0) | 0.93 |
| LDL-P size, nm | 21.6 (0.7) | 21.7 (0.6) | 21.5 (0.7) | 0.28 |
| HDL-P size, nm | 9.2 (0.5) | 9.2 (0.4) | 9.1 (0.5) | 0.13 |
| E2, pg/ml | 31.8 (19.3, 83.1) | 48.4 (21.7, 109.0) | 27.4 (15.6, 47.9) | 0.007 |
| SHBG, nM | 37.0 (24.9, 51.2) | 36.9 (24.3, 51.2) | 37.4 (25.1, 51.3) | 0.77 |
| Testosterone, ng/dl | 32.2 (22.2, 49.15) | 29.7 (20.6, 36.1) | 38.8 (26.3, 53.9) | 0.007 |
| FAI | 3.2 (1.7, 6.1) | 2.5 (1.5, 5.1) | 3.6 (2.1, 6.6) | 0.11 |
Continuous variables were presented as mean (SD) or median (Q1, Q3) while categorical variables were presented as n (%).
a
Only available for 98 participants.