Figure 2. Regional Cerebral Blood Flow Response to Ingestion of Glucose or Fructose.
A, Regional cerebral blood flow (CBF) response to glucose ingestion. B, Regional CBF response to fructose ingestion. The images represent paired t tests for postdrink vs baseline for 20 participants. The blue regions identify the areas in the brain with significantly decreased regional CBF after glucose or fructose ingestion compared with baseline. There were no brain regions with increased regional CBF after either fructose or glucose ingestion. Significance threshold set at P<.05, 2-tailed, family-wise error whole-brain corrected. Z is defined from top to bottom on the Montreal Neurological Institute (MNI) atlas with the origin passing through the anterior commissure- posterior commissure (AC-PC) line. MNI coordinates were used to define brain regions.