Fig. 2.
Effect of unloading and sclerostin antibody treatment on (A) total body BMD, (B) hindlimb BMD, and (C) forelimb BMD. *Significantly different from baseline (p < 0.001). Horizontal bars denote significant differences (p < 0.01) between VEH and SclAbII within loading groups; †p < 0.05 for CON versus HLU within a treatment group. Error bars represent 1 SEM. (One CON-SclAbII and three CON-VEH and animals were excluded from forelimb BMD measurements due to poor positioning on either baseline or follow-up scan.)