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Effect of unloading and sclerostin antibody treatment on serum sclerostin and markers of bone turnover. (A) Sclerostin (vehicle groups only); (B) Osteocalcin; (C) TRACP5b, and (D) CTX1. Horizontal bars designate significant differences between VEH and SclAbII within loading group (p < 0.05). †p < 0.01 CON versus HLU within a treatment group. Error bars represent 1 SEM.
