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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Cancer Res. 2013 Dec 26;74(5):1609–1620. doi: 10.1158/0008-5472.CAN-13-2444

Fig. 5. Immunofluorescence of E-cadherin and β-catenin expression in control (neo) and MUC1 expressing (MUC1) S2-013 cells with and without re-expression of the indicated isoforms of p120 catenin.

Fig. 5

(A) E-cadherin is not stabilized in the absence of p120 catenin in S2-013.Neo cells. Re-expression of p120 isoforms 1A, 3A, 4A in S2-013 cells restored E-cadherin expression. Green indicates E-cadherin staining, Blue are nuclei. (B) β-catenin expression was extremely low in control S2-013 cells that lacked p120 catenin. Expression of MUC1 alone or re-expression of p120 catenin isoforms enhanced slightly the levels of β-catenin at cell junctions. There was a dramatic increase in levels of junctional β-catenin in cells expressing MUC1 and any of the p120 catenin isoforms. β-catenin staining is shown as green and nuclei are blue.