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. 2014 Jun 30;9(6):e99986. doi: 10.1371/journal.pone.0099986

Figure 3. Virally expressed MBII-52 in the NAc regulates cocaine-induced CPP and locomotor activity.

Figure 3

(A) Verification of anatomical placement and viral infection in NAc after LV-MBII-52 EGFP injection; immunostaining for GFP is shown. (B) Virally expressed MBII-52 significantly attenuated cocaine-induced CPP. n = 10, *P<0.05 and **P<0.01. (C) MBII-52 mRNA level in the NAc of mice infected with LV-MBII-52 after cocaine CPP treatment. *P<0.05 and **P<0.01. (D) LV-MBII-52 significantly reduced the locomotor activity of the mice with repeated cocaine administration. n = 10, *P<0.05 and **P<0.01.