Figure 4. Virally expressed 5HT2CR in the NAc regulates cocaine-induced CPP and locomotor activity.

(A) Virally expressed 5HT2CR significantly attenuated cocaine-induced CPP. n = 10, **P<0.01. (B) 5HT2CR mRNA level in the NAc of mice infected with LV-5HT2CR after cocaine CPP treatment. **P<0.01. (C) LV-5HT2CR significantly reduced the locomotor activity of the mice with repeated cocaine administration. n = 10, **P<0.01.