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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Neuropathol Appl Neurobiol. 2014 Feb;40(2):217–220. doi: 10.1111/nan.12060
Case Age Gender MLL2/3 Mutation* PTCH/CTNNB1/TP53/PTEN Status MYC Amplification* OTX2 Amplification* OTX2 Expression Histopathologic Subtype Survival
1 5 Male MLL2: missense (R4852Q) no mutation No No Positive Severe Anaplastic 5 years, alive
2 11 Male MLL2: Frameshift no mutation ND ND Positive Moderate Anaplastic 6 years, alive
3 7 Female MLL2: Nonsense (R4921X); MLL3: Nonsense (R2609X) no mutation Yes No ND Large Cell 3 months, deceased