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. 2014 Jun 30;9(6):e100337. doi: 10.1371/journal.pone.0100337

Table 1. Estimated fetal weight (EFW) from 22 weeks of pregnancy until birth and anthropometric and hormonal characteristics at birth, 1 and 4 years of life between SGA and AGA babies.

Variable SGA AGA p
n = 23 n = 62
Percentiles of EFW
22 weeks of gestation 23.7±27.4 38.6±28.6 0.05
26 weeks of gestation 35.3±33.2 52±32.4 0.08
30 weeks of gestation 14.8±17.9 44.6±32.2 <0.0001
36 weeks of gestation 11.4±16.6 42.7±33.4 <0.0001
Birth percetiles 3.3±2.6 36.6±24.5 <0.0001
Birth
Female gender (%) 13 (56.5) 34 (54.8) 0.89
Gestational age (wk) 38.8±2 38.9±1.7 0.8
Birth weight (g) 2363.3±384.3 2929.5±507.6 <0.0001
Birth weight (z-score) −1.9±0.3 −0.6±0.8 <0.0001
Birth Lenght (cm) 45.5±2.9 48±2.3 <0.0001
Birth Lenght (z-score) −1.9±0.8 −0.6±1 <0.0001
Cranial perimeter (cm) 32.6±1.7 33.8±1.6 0.006
Ponderal index (kg/m3) 24.8±1.8 26.3±3.1 0.01
Sum of folds (mm) 14.2±2.3 16.7±3.5 0.001
Fat Mass - sum of folds (%) 11±2.6 12.9±3.1 0.01
Glucose (mmol/l) 4.7±1.1 4.5±1.1 0.9
Triglyceride (mg/dl) 0.69±0.4 0.5±0.2 0.22
Cord insulin (mUI/l) 4.1±3.5 4.5±5.3 0.87
Cord leptin (ng/ml) 5.5±6.3 6.9±8.2 0.47
QUICKI 0.48±0.1 0.47±0.1 0.89
1 year of age
Weight (kg) 8.7±6 9.3±0.9 0.0006
Weight (z-score) −0.8±0.6 −0.2±0.8 0.0005
Height (cm) 72.7±1.9 73.9±2.3 0.02
Height (z-score) −0.4±0.7 0.08±0.9 0.02
BMI (kg/m2) 16.4±1.1 17±1.1 0.04
BMI (z-score) −0.7±0.9 −0.2±0.8 0.04
Cranial perimeter (cm) 45.7±1.7 45.9±1.5 0.57
Delta weight 1 yr-birth 1.1±0.6 0.4±0.9 0.002
Sum of folds (mm) 28.8±5 30.5±6.5 0.27
Fat Mass - sum of folds (%) 19.5±3.3 20.1±3.4 0.49
Glucose (mmol/l) 4.4±0.5 4.6±0.4 0.14
Insulin (mUI/l) 2.1±1.8 2.3±2.3 0.75
Leptin (ng/ml) 2.9±1 3.7±1.9 0.05
QUICKI 0.51±0.1 0.54±0.2 0.38
4 years of age
Weight (kg) 15.2±1.8 16.3±1.9 0.02
Weight (z-score) −0.1±1.3 0.5±1.3 0.05
Height (cm) 100.3±3.1 102.1±3.6 0.03
Height (z-score) 0.4±1 0.8±1.1 0.1
BMI (kg/m2) 15.1±1.3 15.6±1.2 0.08
BMI (z-score) −0.4±1.1 0.01±1 0.08
Cranial perimeter (cm) 50±1.5 50.3±1.7 0.26
Sum of folds (mm) 28.3±9.2 30±7.3 0.40
Fat Mass - sum of folds (%) 19±4.8 19.7±4.1 0.45
Systolic BP (mmHg) 101.4±10.8 100.4±10.6 0.71
Diastolic BP(mmHg) 51±10.5 55.3±12.7 0.14
Lean Mass (g) 11741.8±932.1 12319.2±1889.2 0.09
Fat Mass (g) 2519.6±1338.2 2723.4±1075 0.5
Bone mineral content (g/cm) 419.2±58 512.4±79.3 0.21
Triglyceride (mg/dl) 0.6±0.1 0.6±0.2 0.95
Total cholesterol (mmol/l) 4.1±0.6 4.1±0.8 0.94
HDL cholesterol (mmol/l) 41.3±24.6 35.1±25 0.36
Leptin (ng/ml) 4.3±3.8 3.8±1.8 0.22
Glucose t0 (mmol/l) 4.2±0.8 4.6±0.5 0.01
Glucose t30 (mmol/l) 7.9±1.6 8.3±1.8 0.38
Glucose t120 (mmol/l) 6.2±1.1 5.6±0.9 0.006
Insulin t0 (mUI/l) 2.4±1.5 3±1.7 0.2
Insulin t30 (mUI/l) 21±15.1 28.1±16.2 0.11
Insulin t120 (mUI/l) 10.2±5.3 9.1±5.1 0.36
QUICKI 0.47±0.09 0.43±0.05 0.06
Insulinogenic index 0.28±0.15 0.40±0.24 0.02
Disposition Index 8.3±5.3 10.2±6.3 0.29