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. 2014 Jun 30;9(6):e101004. doi: 10.1371/journal.pone.0101004

Figure 3. Expression of enzymes associated with serine/glycine metabolism in different molecular breast cancer subtypes.

Figure 3

PHGDH levels were increased in the epithelial component of the HER-2 and TNBC subtypes. PSPH was increased in the tumor epithelium of the TNBC subtype and in the HER-2 stroma. SHMT1 expression was high in the epithelial component of the TNBC subtype and in the stromal component of the luminal-B and HER-2 subtypes. GLDC was high in the epithelial and stromal components of the HER-2 subtype.