Table 9. Multivariate analysis of breast cancer survival.

Included parameters	Disease-free survival			Overall survival
	Hazard ratio	95% CI	P-value	Hazard ratio	95% CI	P-value
T stage			0.010			0.101
T1 versus T2–3	2.245	1.212–4.160		1.656	0.906–3.024
N stage			<0.001			0.004
N0 versus N1–3	2.574	1.513–4.379		2.204	1.284–3.782
Histologic grade			0.271			0.990
I/II versus III	1.365	0.785–2.374		1.004	0.562–1.791
ER status			0.129			0.322
Negative versus Positive	1.849	0.836–4.089		1.495	0.675–3.311
PR status			1.298			0.141
Negative versus Positive	1.298	0.595–2.833		1.839	0.817–4.140
HER-2 status			0.097			0.112
Negative versus Positive	1.645	0.913–2.962		1.638	0.891–3.012
PHGDH in tumor			0.367			0.932
Negative versus Positive	0.754	0.409–1.393		0.973	0.520–1.819
PSPH in tumor			0.069			0.036
Negative versus Positive	1.911	0.952–3.836		2.068	1.049–4.079
PSPH in stroma			0.399			0.024
Negative versus Positive	1.345	0.676–2.677		2.152	1.107–4.184
SHMT1 in stroma			0.141			0.008
Negative versus Positive	1.490	0.876–2.532		2.142	1.219–3.764
GLDC in tumor			1.654			0.634
Negative versus Positive	1.654	0.935–2.925		1.149	0.649–2.033