Table 1. Co-inheritance of SCA-alpha thalassemia and of clinical events.
HbSS-(αα/αα) | HbSS-(αα/α3.7) | HbSS-(α3.7/α3.7) | ||||||
N | Median (Minimum-Maximum) | N | Median (Minimum-Maximum) | N | Median (Minimum-Maximum) | P-values | ||
BMI (kg/m2) | 49 | 17.5 (12.1–26.6) | 27 | 17.7 (12.5–26.7) | 7 | 18.3 (17.0–23.1) | 0.91 | |
Systolic blood pressure (mmHg) | 49 | 108 (86–156) | 29 | 108 (89–135) | 6 | 105.5 (99–116) | 0.71 | |
Diastolic blood pressure (mmHg) | 49 | 56 (41–93) | 29 | 60 (47–60) | 6 | 60.5 (45–70) | 0.62 | |
No. of vaso-occlusive pain crises/year | 77 | 2 (0–15) | 35 | 2 (0–40) | 9 | 1 (1–4) | 0.31 | |
Overt Stroke | YES | 6 | - | 1 | - | 1 | - | 0.48 |
NO | 65 | - | 33 | - | 7 | - | ||
No. of consultations/year | 70 | 2 (0–12) | 31 | 1 (0–12) | 9 | 1 (0–4) | 0.52 | |
No. of hospitalisations/year | 70 | 1 (0–10) | 33 | 1 (0–10) | 9 | 1 (0–9) | 0.28 |