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. 2014 Jun 30;9(6):e100516. doi: 10.1371/journal.pone.0100516

Table 1. Co-inheritance of SCA-alpha thalassemia and of clinical events.

HbSS-(αα/αα) HbSS-(αα/α3.7) HbSS-(α3.7/α3.7)
N Median (Minimum-Maximum) N Median (Minimum-Maximum) N Median (Minimum-Maximum) P-values
BMI (kg/m2) 49 17.5 (12.1–26.6) 27 17.7 (12.5–26.7) 7 18.3 (17.0–23.1) 0.91
Systolic blood pressure (mmHg) 49 108 (86–156) 29 108 (89–135) 6 105.5 (99–116) 0.71
Diastolic blood pressure (mmHg) 49 56 (41–93) 29 60 (47–60) 6 60.5 (45–70) 0.62
No. of vaso-occlusive pain crises/year 77 2 (0–15) 35 2 (0–40) 9 1 (1–4) 0.31
Overt Stroke YES 6 - 1 - 1 - 0.48
NO 65 - 33 - 7 -
No. of consultations/year 70 2 (0–12) 31 1 (0–12) 9 1 (0–4) 0.52
No. of hospitalisations/year 70 1 (0–10) 33 1 (0–10) 9 1 (0–9) 0.28