Table 2. Hematological indices of SCA patients and controls (HbAA and HbAS).
HbAA | HbAS | HbSS | |||||
Haematological indices | N | Median (Minimum-Maximum) | N | Median (Minimum-Maximum) | N | Median (Minimum-Maximum) | P-values |
RBC (million cells/µl) | 64 | 4.4 | 36 | 4.6 | 149 | 2.7 | 0.01 |
(2–9.3) | (2.1–9.3) | (1.7–5.5) | |||||
Hb (g/dl) | 65 | 13.2 | 38 | 12.7 | 150 | 7.7 | <0.0001 |
(7.9–19.5) | (6.9–18.7) | (3.3–14.5) | |||||
MCV (fL) | 65 | 81 | 38 | 79 | 150 | 82 | 0.021 |
(64–95) | (56–102) | (66–112) | |||||
CCMH (g/dl) | 64 | 36.3 | 36 | 33.8 | 148 | 33.9 | 0.021 |
(28.6–45.7) | (29.1–45.2) | (26.6–54.3) | |||||
WBC (X109/L) | 65 | 5.1 | 38 | 4.8 | 150 | 12.4 | <0.0001 |
(4.4–6.0) | (2–19) | (2.9–42.4) | |||||
Lymphocyte count (X109/L) | 64 | 2.1 | 38 | 2.2 | 130 | 5.1 | <0.0001 |
(2.8–24.4) | (0.2–9) | (1.2–21.6) | |||||
Monocyte count (X109/L) | 64 | 0.6 | 38 | 0.5 | 130 | 1.2 | 0.001 |
(0.4–0.8) | (0.3–2.3) | (0.4–7.8) | |||||
Platelet level (X 109/L) | 65 | 224 | 29 | 219 | 149 | 354 | 0.001 |
(174–651) | (137–371) | (110–802) | |||||
HbF (%) | 39 | 5.9 | 17 | 7.3 | 143 | 11.1 | 0.002 |
(0–21.6) | (0–17.1) | (0–29.3) | |||||
HbA2 (%) | 58 | 3.2 | 32 | 2.8 | 147 | 3.8 | 0.003 |
(0.1–5) | (0–7.2) | (1.6–18.2) |