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. 2014 Jun 30;9(6):e100516. doi: 10.1371/journal.pone.0100516

Table 2. Hematological indices of SCA patients and controls (HbAA and HbAS).

HbAA HbAS HbSS
Haematological indices N Median (Minimum-Maximum) N Median (Minimum-Maximum) N Median (Minimum-Maximum) P-values
RBC (million cells/µl) 64 4.4 36 4.6 149 2.7 0.01
(2–9.3) (2.1–9.3) (1.7–5.5)
Hb (g/dl) 65 13.2 38 12.7 150 7.7 <0.0001
(7.9–19.5) (6.9–18.7) (3.3–14.5)
MCV (fL) 65 81 38 79 150 82 0.021
(64–95) (56–102) (66–112)
CCMH (g/dl) 64 36.3 36 33.8 148 33.9 0.021
(28.6–45.7) (29.1–45.2) (26.6–54.3)
WBC (X109/L) 65 5.1 38 4.8 150 12.4 <0.0001
(4.4–6.0) (2–19) (2.9–42.4)
Lymphocyte count (X109/L) 64 2.1 38 2.2 130 5.1 <0.0001
(2.8–24.4) (0.2–9) (1.2–21.6)
Monocyte count (X109/L) 64 0.6 38 0.5 130 1.2 0.001
(0.4–0.8) (0.3–2.3) (0.4–7.8)
Platelet level (X 109/L) 65 224 29 219 149 354 0.001
(174–651) (137–371) (110–802)
HbF (%) 39 5.9 17 7.3 143 11.1 0.002
(0–21.6) (0–17.1) (0–29.3)
HbA2 (%) 58 3.2 32 2.8 147 3.8 0.003
(0.1–5) (0–7.2) (1.6–18.2)