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. 2014 Jun 30;9(6):e101215. doi: 10.1371/journal.pone.0101215

Table 2. Demographic comparison between survivors and non-survivors with sepsis or severe sepsis.

Variables Survivor (n = 40) Non-survivor (n = 26) p
Age (Mean ± SD) 62.6±14.8 65.5±15.3 0.443
Male/Female 41584 41407 0.632
Co-morbidity [No. (%)]
cardiovascular disease 10 (25.0) 17 (65.4) 0.001
diabetes mellitus 12 (30.0) 10 (38.4) 0.476
Primary diagnosis [No. (%)] 0.713
major abdominal surgery 21 (52.5) 15 (57.7)
intestinal obstruction 4 (10.0) 4 (15.4)
intestinal perforation 6 (15.0) 4 (15.4)
lithangiuria 2 (5.0) 0 (0)
others 7 (17.5) 3 (11.5)
Infection site [No. (%)] 0.377
abdomen 30 (75.0) 20 (76.9)
respiratory 2 (5.0) 3 (11.5)
urine 2 (5.0) 0 (0)
blood 4 (10.0) 3 (11.5)
mixed 2 (5.0) 0 (0)
Pathogen type [No. (%)] 0.109
Gram-negative 12 (30.0) 3 (11.5)
Gram-positive 13 (32.5) 8 (30.8)
fungus 1 (2.5) 4 (15.4)
mixed 14 (35.0) 11 (42.3)
APACHE II score [median (IQR)] 16.5 (13.0, 20.8) 20.5 (16.0, 25.3) 0.015
SOFA score [median (IQR)] 6.0 (3.0, 9.8) 9.5 (5.5, 12.0) 0.069
MODS score [median (IQR)] 5.0 (2.0, 7.0) 6.0 (4.0, 7.3) 0.166
IL-6 69.6 (1.2, 180.5) 140.1 (6.9, 557.2) 0.036
IL-10 14.6 (8.5, 25.5) 24.3 (1.5, 32.4) 0.041
eHSPA12B 0.9 (0.5, 1.3) 2.9 (1.4, 6.7) <0.001

SD standard deviation, IQR inter-quartile range, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, MODS Multiple Organ Dysfunction Syndrome, MV mechanical ventilation, ICU intensive care unit, IL-6 interleukin 6, IL-10 interleukin 10, eHSPA12B extracellular heat shock protein A12B.