Table 2. Demographic comparison between survivors and non-survivors with sepsis or severe sepsis.
Variables | Survivor (n = 40) | Non-survivor (n = 26) | p |
Age (Mean ± SD) | 62.6±14.8 | 65.5±15.3 | 0.443 |
Male/Female | 41584 | 41407 | 0.632 |
Co-morbidity [No. (%)] | |||
cardiovascular disease | 10 (25.0) | 17 (65.4) | 0.001 |
diabetes mellitus | 12 (30.0) | 10 (38.4) | 0.476 |
Primary diagnosis [No. (%)] | 0.713 | ||
major abdominal surgery | 21 (52.5) | 15 (57.7) | |
intestinal obstruction | 4 (10.0) | 4 (15.4) | |
intestinal perforation | 6 (15.0) | 4 (15.4) | |
lithangiuria | 2 (5.0) | 0 (0) | |
others | 7 (17.5) | 3 (11.5) | |
Infection site [No. (%)] | 0.377 | ||
abdomen | 30 (75.0) | 20 (76.9) | |
respiratory | 2 (5.0) | 3 (11.5) | |
urine | 2 (5.0) | 0 (0) | |
blood | 4 (10.0) | 3 (11.5) | |
mixed | 2 (5.0) | 0 (0) | |
Pathogen type [No. (%)] | 0.109 | ||
Gram-negative | 12 (30.0) | 3 (11.5) | |
Gram-positive | 13 (32.5) | 8 (30.8) | |
fungus | 1 (2.5) | 4 (15.4) | |
mixed | 14 (35.0) | 11 (42.3) | |
APACHE II score [median (IQR)] | 16.5 (13.0, 20.8) | 20.5 (16.0, 25.3) | 0.015 |
SOFA score [median (IQR)] | 6.0 (3.0, 9.8) | 9.5 (5.5, 12.0) | 0.069 |
MODS score [median (IQR)] | 5.0 (2.0, 7.0) | 6.0 (4.0, 7.3) | 0.166 |
IL-6 | 69.6 (1.2, 180.5) | 140.1 (6.9, 557.2) | 0.036 |
IL-10 | 14.6 (8.5, 25.5) | 24.3 (1.5, 32.4) | 0.041 |
eHSPA12B | 0.9 (0.5, 1.3) | 2.9 (1.4, 6.7) | <0.001 |
SD standard deviation, IQR inter-quartile range, APACHE II Acute Physiology and Chronic Health Evaluation II, SOFA Sequential Organ Failure Assessment, MODS Multiple Organ Dysfunction Syndrome, MV mechanical ventilation, ICU intensive care unit, IL-6 interleukin 6, IL-10 interleukin 10, eHSPA12B extracellular heat shock protein A12B.