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. 2014 Jun 30;9(6):e101390. doi: 10.1371/journal.pone.0101390

Table 2. Univariate and multivariate survival analyses for BCSS and RFS.

Variables BCSS RFS
Univariate Multivariate Univariate Multivariate
P HR 95% CI P P HR 95% CI P
Age, year ≤50 vs.>50 0.356 1.911 0.768–4.755 0.164 0.582 1.047 0.554–1.982 0.887
TNM stage Stage I & II vs. Stage III 0.002 4.217 1.141–15.579 0.031 <0.001 3.554 1.467–8.609 0.005
Lymphovascular invasion Negative vs. Positive 0.060 1.920 0.397–9.277 0.417 0.039 1.151 0.398–3.331 0.795
ER status Negative vs. Positive 0.001 0.493 0.126–1.920 0.308 0.009 0.748 0.269–2.082 0.578
PR status Negative vs. Positive 0.001 0.560 0.195–1.610 0.282 0.004 0.644 0.283–1.465 0.294
HER-2 status Negative vs. Positive 0.045 1.121 0.350–3.595 0.847 0.061 1.158 0.513–2.613 0.724

Abbreviations: BCSS, breast cancer-specific survival; RFS, recurrence/metastasis-free survival; HR, hazard ratio; CI, confidence interval; TNM, tumor, node, metastasis; ER, estrogen receptor; PR, progesterone receptor; HER-2, human epidermal growth factor receptor 2

Bold values denote P<0.05.