Table 4. Top results in the global meta-analysis.
CHR | Gene† | SNP | BP‡ | A1 | p | p(R) | OR | OR(R) | Q | I |
9q31.1 | LINC00587 | rs1930551* | 104380162 | T | 0.000117 | 0.008854 | 1.42 | 1.43 | 0.1005 | 56.48 |
9q31.1 | LINC00587 | rs10990158 | 104335927 | T | 0.000118 | 0.010900 | 1.41 | 1.42 | 0.0895 | 58.57 |
7q31.1 | NRCAM | rs2041001* | 107870335 | G | 0.000153 | 0.002704 | 1.46 | 1.46 | 0.1989 | 38.08 |
10q25.3 | ABLIM1 | rs941853 | 116189165 | A | 0.000196 | 0.009045 | 0.79 | 0.78 | 0.125 | 51.92 |
7p15.1 | LOC402644 | rs4722778 | 28278588 | G | 0.000253 | 0.025260 | 0.82 | 0.82 | 0.0617 | 64.11 |
12q21.33 | LINC00615 | rs10506984* | 89217396 | G | 0.000347 | 0.000347 | 0.83 | 0.83 | 0.6274 | 0.00 |
9q31.1 | LINC00587 | rs7039568 | 104361604 | T | 0.000417 | 0.030730 | 1.37 | 1.40 | 0.0532 | 65.92 |
9q31.1 | LINC00587 | rs16921774* | 104336206 | T | 0.000479 | 0.025540 | 1.36 | 1.38 | 0.0743 | 61.54 |
9q31.1 | LINC00587 | rs10990136 | 104298657 | T | 0.000831 | 0.039330 | 1.35 | 1.37 | 0.0581 | 64.85 |
5q21.1 | ST8SIA4 | rs2120913* | 100096374 | A | 0.000852 | 0.000852 | 0.85 | 0.85 | 0.8767 | 0.00 |
9q31.1 | LINC00587 | rs7024470 | 104361506 | G | 0.000941 | 0.030740 | 1.34 | 1.36 | 0.0777 | 60.87 |
CHR: Chromosome; BP: Base pair position; SNP: Single Nucleotide Polymorphism; A1: Reference allele (minor allele); p: Fixed-effects p-value; p(R): Random-effects p-value; OR: Fixed-effects Odds Ratio; OR(R): Random-effects Odds Ratio; Q: p-value for heterogeneity of OR; I: effect size for heterogeneity of OR.
*SNPs selected by two-locus association analyses in the NXC-GWAS sample.
The nearest gene or the gene where the SNP is located.
According to UCSC genome browser (NCBI36/hg18) and dbSNP build 130.