Table 5. Results of previously reported SNPs that were successfully genotyped or imputed in our analysis.
| NXC-GWAS | |||||||||
| CHR | Gene† | SNP | Reported allele | Reported OR | Reference | F A | F U | OR | p |
| 1q25.3 | LAMC1 | rs10911251 | A | 1.09 | [10] | 0.570 | 0.553 | 1.07 | 0.4898 |
| 1q41 | DUSP10 | rs6691170 | G | 0.94 | [6] | 0.626 | 0.647 | 0.91 | 0.2945 |
| 1q41 | DUSP10 | rs6687758 | A | 0.92 | [6] | 0.797 | 0.817 | 0.88 | 0.2157 |
| 2q32.3 | OBFC2A | rs11903757 | C | 1.16 | [10] | 0.142 | 0.139 | 1.02 | 0.8047 |
| 3q26.2 | MYNN | rs10936599 | C | 1.08 | [6] | 0.821 | 0.786 | 1.25 | 0.0386 |
| 8q23.3 | EIF3H | rs16892766 | A | 0.92 | [14] | 0.905 | 0.926 | 0.75 | 0.0575 |
| 8q24 | DQ515899 | rs10505477 * | A | 1.17 | [15] | 0.571 | 0.508 | 1.28 | 0.0019 |
| 8q24.21 | DQ515899 | rs6983267 | G | 1.21 | [12] | 0.571 | 0.508 | 1.28 | 0.0019 |
| 9p24 | UHRF2 | rs719725 | A | 1.07 | [15] | 0.598 | 0.605 | 0.97 | 0.7259 |
| 10p14 | BC031880 | rs10795668 | A | 0.89 | [14] | 0.304 | 0.299 | 1.02 | 0.7826 |
| 11q13.4 | POLD3 | rs3824999 | G | 1.08 | [5] | 0.534 | 0.487 | 1.20 | 0.0242 |
| 11q23 | LOC120376 | rs3802842 | A | 0.90 | [11] | 0.702 | 0.709 | 0.96 | 0.6972 |
| 12q13.13 | LARP4 | rs7136702 | C | 0.94 | [6] | 0.612 | 0.647 | 0.85 | 0.0713 |
| 14q22.2 | BMP4 | rs4444235 | C | 1.09 | [7] | 0.539 | 0.493 | 1.20 | 0.0435 |
| 15q13.3 | SCG5 | rs16969681 | C | 0.84 | [13] | 0.876 | 0.900 | 1.27 | 0.0618 |
| 16q22.1 | CDH1 | rs9929218 | A | 0.91 | [7] | 0.262 | 0.274 | 0.93 | 0.5028 |
CHR: Chromosome; SNP: Single Nucleotide Polymorphism. The last four columns show the allele reported frequency in cases (F A), in controls (F U) and, the p and the Odds Ratio (OR) values obtained in the NXC-GWAS sample.
In bold type, SNPs with a nominal p-value below 0.05.
†
The nearest gene or the gene where the SNP is located.
*SNPs genotyped (not imputed).