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Effect of injury and E2 on TGFβ1 and LOX gene expression in the vaginal wall. TGFβ1 (A) and LOX (B) mRNA levels were quantified in vaginal tissues from noninjured (NI) or injured (Inj) ovariectomized vehicle- (Veh) or E2-treated animals at 4 and 21 days after injury. Data were normalized to B2M and represent mean ± SEM of six animals in each group. *P < 0.05 compared with NI. **P < 0.05 compared with controls, two-way ANOVA.
