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. 2014 Feb 26;90(4):75. doi: 10.1095/biolreprod.114.117531

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© 2014 by the Society for the Study of Reproduction, Inc.

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FIG. 3 — Functional annotation of SRC-2-dependent progesterone responsive genes in the murine uterus. A) Unique SRC-2-dependent genes that are induced or repressed by P4 were analyzed for annotated gene function and similarities using the functional annotation and classification tools provided by DAVID Bioinformatics Resources, 6.7 (NIAID/NIH). Comparative enrichment of GO terms in the SRC-2-dependent P4 gene list is shown. The X-axis represents the percentage of genes enriched for individual GO term (P < 0.01). B) List of genes grouped based on the presence of similar protein domains. The X-axis represents the percentage of genes classified for each group (P < 0.05). C) Table illustrating unique genes that have bHLH protein domain is shown. The fold change indicates the fold reduction (−) in P4 induction of each gene when SRC-2 expression levels are markedly diminished.